- ANTI-INFECTIVE & ANTIBACTERIAL DRUGS
- DERMATOLOGICAL DRUGS
- Pharmaceutical Form : Gel
- Composition : Clindamycin ( Phosphate ) 10 mg / 1 gr
- Active Substance : Clindamycin
Although clindamycin phosphate is inactive in vitro , rapid in vivo hydrolysis converts
This compound to the antibacterially active clindamycin .
INDICATIONS AND USAGE
CLINDAMYCIN Topical gel is indicated in the treatment of acne vulgaris
CLINDAMYCIN Topical gel is contraindicated in individuals with a history of hypersensitivity
To preparations containing clindamycin or lincomycin , a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
CLINDAMYCIN should be prescribed with caution in atopic individuals . In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate .
Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents . Therefore it should be used with caution in patients receiving such agents .
Pregnancy category B :
This drug should be used during pregnancy only if clearly needed .
Nursing Mothers :
It is not known whether clindamycin is excreted in human milk following use of CLINDAMYCIN . Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother .
Pediatric use :
Safety and effectiveness in pediatric patients under the age of 12 have not been established .
SIDE EFFECTS :
Burning – Itching- Dryness – Erythema – Peeling .
Abdominal pain and gastro intestinal disturbance as well as gram negative follculitis have also been reported in association with the use of topical formulations of clindamycin
DOSAGE AND ADMINISTRATION
Apply a thin film of Topical gel twice daily to affected area .
Store at controlled room temperatare 20 – 25 ºC
Tube 20 g– 50 g