CLINDAMYCIN-MEDICO

  • Therapeutic Category
    • DERMATOLOGICAL DRUGS
    • ANTI-INFECTIVE & ANTIBACTERIAL DRUGS
  • Pharmaceutical Form : Gel
  • Composition : Clindamycin ( Phosphate ) 10 mg / 1 gr
  • Active Substance : Clindamycin

Properties   :

 Although clindamycin phosphate is inactive in vitro , rapid in vivo hydrolysis converts

This compound to the antibacterially active clindamycin .

INDICATIONS AND USAGE

CLINDAMYCIN  Topical gel is indicated in the treatment of acne vulgaris

CONTRAINDICATIONS

CLINDAMYCIN Topical gel is contraindicated in individuals with a history of  hypersensitivity

To preparations containing clindamycin or lincomycin , a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.

PRECAUTIONS

CLINDAMYCIN should be prescribed with caution in atopic individuals . In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate .

DRUG INTERACTIONS

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents . Therefore it should be used with caution in patients receiving such agents .

Pregnancy category B :

This drug should be used during pregnancy only if clearly needed .

Nursing Mothers :

It is not known whether clindamycin is excreted in human milk following use of CLINDAMYCIN . Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother .

Pediatric use :

Safety and effectiveness in pediatric patients under the age of 12 have not been established .

SIDE EFFECTS :

Burning – Itching- Dryness – Erythema – Peeling .

Abdominal pain and gastro intestinal disturbance as well as gram negative follculitis have also been reported in association with the use of topical formulations of clindamycin

DOSAGE AND ADMINISTRATION

Apply a thin film of Topical gel twice daily to affected area .

Store at controlled room temperatare  20 – 25 ºC

PACKING :

Tube 20 g– 50 g