NAPHANTAN

  • Therapeutic Category
    • OPHTHALMOLOGICAL DRUGS
    • OTHER OPHTHALMOLOGICAL DRUGS
  • Pharmaceutical Form : Eye Drops
  • Composition : Antazoline Sulphate 5 mg + Naphazoline Nitrate 0.25 mg /1 ml
  • Active Substance : Antazoline Sulphate + Naphazoline Nitrate

Properties :
Antazoline : antiallergic , competitively blocks the H1 – receptors in the effector cells and thus
reduces the effects of the histamine released in the tissues .
Naphazoline : a sympathommetic , relives inflammatory irritations of the conjunctiva .
so Naphantan is used for the short-term symptomatic treatment of allergic ocular manifestations.

Indications :
Naphantan is indicated in the following cases :
– Irritative conjunctivitis .
– Allergic conditions of the conjunctiva , especially hay-fever , and vernal conjunctivitis .

Contraindications :
Naphantan is contraindicated in the following cases :
– Hypersensitivity to any of its components .
– eye dryness , especially kerato conjunctivitis siccus ( sjogren’s syndrome) .
– Patients with a risk of narrow-angle glaucoma or who are suspectible to it .
– Children under 5 years .
– Concomitant use with MAO inhibitors .

Precautions :
-This preparation is not indented for long-term use .
-Naphantan should be used with caution in case of increase intraocular pressure or rhinitis sicca and
in patients with high blood pressure , cardiac arhythmia , diabetes mellitus or hyperthyroidism .

Adverse reactions :

Increase intraocular pressure ( narrow-angle glaucoma ) , mydriasis , central
stimulation , a slight transient burning sensation may sometimes be observed immediately after
instillation of the drops .
Headache , drowsiness , dizziness and tachycardia may appear in rare cases , especially in children .

Dosage & Administration :
Adults : instill one drop (3 – 4 )times daily into the conjunctival sac .
Children (5 – 12) years and elders : the dosage should not exceed one drop (2 – 3) times daily .
The vasoconstrictor effect begins (5 – 12) minutes and lasts (2 – 6) hours .

Notes :

*Naphantan with contact lenses should not be used .
* Once opend , the drops must not be used for longer than one month .
* Store up to 30°C .

Packaging : bottle of 10 ml.